HLA-MISMATCHED STEM CELL MICROTRANSPLANT PROLONGED OVERALL SURVIVAL AND PROMOTED IMMUNOLOGICAL RECONSTITUTION FOR MULTIPLE MYELOMA

HLA-mismatched stem cell microtransplant prolonged overall survival and promoted immunological reconstitution for multiple myeloma

BackgroundDespite advances in the treatment of multiple myeloma, a proportion of patients still hardly achieve desired prognosis.Although microtransplant (MST) has proved promising results in treating several hematological malignancies, it has not been studied Table Runners in multiple myeloma.MethodsWe performed a retrospective analysis of multipl

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Transcriptome sequencing and metabolome analysis of food habits domestication from live prey fish to artificial diets in mandarin fish (Siniperca chuatsi)

Abstract Background As economical traits, food habits domestication can reduce production cost in aquaculture.However, the molecular mechanism underlying food habits domestication has remained elusive.Mandarin fish (Siniperca chuatsi) only feed on live prey fish and refuse artificial diets.In the present study, we domesticated mandarin fish to feed

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A STUDY TO EVALUATE AND COMPARE THE EFFICACY AND SAFETY OF TOPICAL CYCLOSPORINE-A 0.5% WITH TOPICAL PLACEBO (ARTIFICIAL TEARS) IN ALLEVIATING THE CLINICAL FEATURES ASSOCIATED WITH VERNAL KERATOCONJUNCTIVITIS

Introduction: Vernal keratoconjunctivitis is a severe, typically seasonal recurrent ocular inflammatory disorder.Topical cyclosporine-A is inhibitory to many T-cell dependent inflammatory mechanisms which Black Clover are likely to play role in treatment of vernal keratoconjunctivitis.Methodology: The study was conducted on 100 patients of vernal k

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